Hops Purchase & Information
Alternative Names
Asperge Sauvage, Couleuvrée Septentrionale, Couleuvrée, Common Hops, European Hops, Hopfenzapfen, Hop Strobile, Hop, Houblon, Lúpulo, Lupulin, Lupuli Strobulus, Pi Jiu Hua, Salsepareille Indigène, Vigne du Nord
Scientific Name
Humulus Lupulus
Why Do People Use Hops?
The oral preparations of Humulus lupulus (Hops), like hops powder, can be used for anxiety, restlessness, cancer, tuberculosis, hyperlipidemia, insomnia and other sleep disorders, excitability, tension, intestinal cramps, as an appetite stimulant, and irritability, as a bitter tonic, diuretic, for indigestion and to stimulate lactation. Other oral purposes of hops powder utilization are for breast cancer, prostate cancer, menopausal symptoms, ovarian cancer, tuberculosis, hyperlipidemia, nervousness, attention deficit-hyperactivity disorder (ADHD), intestinal cramps, cystitis, neuralgia, mucous colitis and priapism.
Topically - Humulus lupulus can be applied to the skin as an antibacterial and for leg ulcers.
For foods and beverages - The oil extract of hops is used as a flavoring agent in a number of commercial products. Whereas strobile is generally used for brewing beer.
In manufacturing Practices - In many skin lotions and creams, hops is added as a vital ingredient.
Is It Safe To Use?
Likely Safe - Oral consumption of hops in foods items is considered safe. Both Hops and its oil are ranked as Generally Recognized as Safe (GRAS) in the United States. In addition, appropriate utilization of hops for medicinal purpose is also considered safe.
Avoid in Lactation & Pregnancy - Breastfeeding and pregnant females should discontinue any type of usage of hops as there is inadequate information available in this regard.
How Effective Is Hops?
There is not enough information available to rate the effectiveness of hops for following conditions:
Insomnia - Mixture of different products, containing 187 mg of valerian extract and 41.9 mg of hops extract per tablet, used as two tablets at bedtime may enhance the subjective sleep latency as compared to placebo after treatment for 28 days. Still more confirmations are required to rate effectiveness of hops for this purpose.
How Hops Works?
The most effective part of Humulus lupulus include female, dried flowering part (strobile). Hops consists of a number of active flavonoids that include isoprenylated flavanone isoxanthohumol, isoprenylated chalcone xanthohumol and other flavonoids for example, rutin, 8- quercetin, prenylnaringenin (8-PN) and astragalin.
The xanthohumol constituent exists in a range of 0.1%-1% in lupulin, also known as hops resin. Xanthohumol may have a few pharmacological impacts including potential anticancer effects. According to clinical experiments, it has antioxidant and anti-inflammatory impacts as well.
Some studies also suggest that xanthohumol and hops constituents are useful for prostate cancer. In vitro examinations recommend that a derivative of xanthohumol can affect malignant prostate growth cells and apoptosis in prostate hyperplasia. These constituents appear to increase the expression pro-apoptotic proteins p53 and Bax. The constituents also appear to lessen the NF-kappaB activation.
In animal models of obesity and diabetes, xanthohumol enhances glucose and lipid metabolism and activates the nuclear receptor farnesoid X receptor (FXR).
The hops isoxanthohumol and flavonoids 8-PN are thought to have mild estrogenic reactions. The 8-PN flavonoid is accounted for similar estrogen-binding limit as the isoflavone genistein, which is exist in soy. The 8-PN flavonoid ties to both alpha and beta estrogen receptors, yet with a higher affinity for the beta-estrogen receptor.
Hops powder also appears to reduce the level of luteinizing hormone in mice that have their ovaries removed.
A few hops flavonoids repress aromatase in vitro. The strongest aromatase inhibitor is 8-PN, followed by xanthohumol and isoxanthohumol individually. This recommends that these mixes may have some anti-estrogenic effects as well, in addition estrogenic action.
Prenylated derivatives of 1-acylphloroglucinol including isohumulones, humulone, lupulone and others are responsible of the bitter flavor of Humulus lupulus.
Clinical experiments suggest hops powder may have anti-proliferative properties and potential chemo-protective effects against ovarian cancer and breast cancer.
What Are The Side Effects /Adverse Reactions of Hops?
Possible allergic side effects caused by topical usage of hops include contact dermatitis.
How Hops Interacts With Other Herbs and Supplements?
Sedative Containing Properties Herbs & Supplements - Combination of herbs containing sedative properties and hops powder may enhance adverse and therapeutic effects. Supplements in this category include calamus, 5-HTP, catnip, California poppy, yerba mansa, kava, Jamaican dogwood, valerian, skullcap and some other herbs as well.
How Hops Interacts With Drugs?
Alcohol (Ethanol) - Interaction rating between alcohol (ethanol) and Humulus lupulus is moderate, so be careful about this mixture. This blend of products can potentiate alcohol’s sedative impact on human body.
CNS Depressants - Interaction rating between hops and drugs containing CNS depressant activity is moderate, so be careful about this combination. This combination may cause adverse and additive therapeutic impacts in human being body.
How Hops Interacts With Foods?
Alcohol - Consumption of hops powder with alcoholic food items can potentiate the sedative effects.
How Hops Interacts With Lab Tests?
No lab test seems to interact with Humulus lupulus.
How Hops Interacts With Diseases and Conditions?
Depression - Hops may effect the rate of depression.
Surgery - Hops powder maybe responsible for depressing the activity of CNS. When hops is used with blend of anesthesia and different drugs, it may cause additive CNS depression impacts after and during surgical procedures. So, such patients are advised to stop using hops preparations a minimum two weeks before their suggested surgical operations.
What Should Be the Dose/Administration of Hops?
ORAL For insomnia, mixture of various products, which consist of 41.9 mg of hops extract and 187 mg of valerian extract per tablet, is used in the dose of two tablets at bedtime for 28 days.
Comments
None.
General Certificate of Analysis (COA)
Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.
