Atractylodes Purchase & Information
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Why Do People Use Atractylodes?
Many people use Atractylodes powder for stomachache, indigestion, edema, abdominal distension, diarrhea, cancer-related cachexia, anorexia, rheumatism and dust mite-related allergic reactions.
Is It Safe To Use?
Possibly safe - When atractylodes constituent atractylenolide is utilized appropriately and orally. Some of clinical findings propose that taking the constituent atractylenolide in a dose of about 1.32 grams every day for continually 7 weeks in balanced dosage is safe and doesn’t show huge side effects.
Regarding safety of other atractylodes products there is insufficient reliable information available.
Pregnancy and Lactation - Atractylodes macrocephala usage should be avoided as there is insufficient reliable information available for subject.
How Effective Is Atractylodes?
Lack of Reliable Information for Cachexia - Some clinical findings demonstrate that taking an isolated atractylodes powder constituent 1.32 grams per day enhances functional capability and appetite in affected persons with gastric cancer-related cachexia. More proof is required about the use atractylodes powder for this utilization.
How Atractylodes Works?
Rhizome is the most commonly used part of atractylodes. The rhizomes related atractylodes species consist number of constituents, which may include sesquiterpenoids, for example, atractylon and atractylenolides, hinesol and beta-eudesmol contained essential oild and L-phenylalanine.
Stir frying atractylodes rhizome changes the sesquiterpene content. After this atractylon level reduce while atractylenolide II and III level increases. Stir frying process us used to degrading Atractylon to atractylenolide II and III.
Atractylon is more cytotoxic to normal and cancer cells as compare to atractylodes II and III. Therefore, cooking or stir fry is thought to reduce the potential toxicity of products of atractylodes. Atractylon and Atractylenolide I constituents are thought to have anticancer reactions by impelling cytotoxic impacts and apoptosis against cancer cell and leukemia. Atractylenolide II and III don't appear to have anticancer impacts in similar ways. Atractylenolide I seems to enhance appetite and functional status in cancer affected persons with cachexia, perhaps by diminishing interleukin 1 (IL-1) levels, expanding tumor putrefaction variable (TNF) levels, and reducing proteolysis-inducing fators (PIF). Atractylodes is utilized as a part of Traditional Chinese Medicine (TCM) and Japanese (Kampo) for conditions pertaining to gastrointestinal. Some researches propose that concentrates of atractylodes may inhibit gastric emptying. The beta-eudesmol constituent appears to have a H2-antagonist impact. Hinesol and Beta-eudesmol appear to boost intestinal motility.
An atractylodes constituent (12E,6E)-tetradecadiene-8, 3-diol diacetate (TDEYA) and 10-diyne-1 additionally appears to defend against gastric mucosa harm brought by indomethacin. This constituent may protect from oxygen radical damage, which can result in gastric mucosa damage, by decreasing activity of xanthine oxidase. A few atractylodes species of animal may likewise adjust the intestinal immune system. Glycoproteins concentrate from Atractylodes macrocephala also strengthen lymphocyte and slpenocytes multiplication, cytokine secretion and antibody product. Atracylodes additionally has anti-inflammatory action. Concentrates of japonica, Atractylodes macrocephala and lancea appear to have cyclooxygenase (COX)-1 and COX-2 inhibitory action. A lipophilic concentrate of Atractylodes lancea additionally seems to inhibit 5-lipoxygenase. This activity appears because of to the atractylochromene and constituents atractylon.
The atractylenolide I and III may also reduce levels of TNF-alpha in lipopolysaccharide-stimulated in vitro; on the other hand, atractylenolide I seems to be most strong inhibitor of TNF-alpha as compare to atractylenolide III. Atractylodes may have action against HIV protease and antifungal activity. Concentrate ofmethanolic Atractylodes ovata rhizome has in vitro reaction for the dust mites Dermatophagoides pterronyssinus and Dermatophagoides farinae. The atractylon and sesquiterpenoids atractylenolide III are the action constituents for these vermin. These more dangerous than chemicals and DEET, for example, benzyl benzoate against dust mites.
What Are The Side Effects /Adverse Reactions of Atractylodes?
Allergy could be the reason by why some people can’t tolerate atractylodes powder. Family member of this family consist of chrysanthemums, ragweed, daisies, marigolds and other herbs. In some experiments, those people who took the isolated atractylodes constituent atractylenolide I showed some side effects like nausea, bad taste and dry mouth.
How Atractylodes Interacts With Other Herbs and Supplements?
How Atractylodes Interacts With Drugs?
How Atractylodes Interacts With Foods?
How Atractylodes Interacts With Lab Tests?
How Atractylodes Interacts With Diseases and Conditions?
Cross-Allergenicity - Allergic reactions could be caused by Atractylodes. Family members of Compositae species include chrysanthemums, ragweed, daisies, marigolds and some other herbs.
What Should Be the Dose/Administration of Atractylodes?
ORAL For cachexia, the atractylodes constituent atractylenolide I 1.32 grams per day has been utilized.
In Traditional Chinese Medicine (TCM) Atractylodes is normally used for treating lung cancer and complications of peritoneal dialysis in patients suffering from chronic renal failure.
General Certificate of Analysis (COA)
Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.