Broccoli Purchase & Information
Brassica Oleracea Italica Group, Brocoli, Brócoli, Broccoli Flower, Calabrese, Purple Sprouting Broccoli CAUTION: Please refer to separate listings for Ascorbigen, Indole-3-carbinol, Sulforaphane
Brassica Oleracea (Italica Group)
Why Do People Use Broccoli?
Oral preparations of Brassica oleracea (Broccoli), like broccoli powder, are used for boosting immune function and preventing cancer.
Is It Safe To Use?
Likely Safe - Oral consumption of broccoli is thought to safe when taken in amounts found in food items.
Likely Safe for Pregnant and Breastfeeding Mothers - Oral consumption of broccoli in amounts found in food amounts seems safe to use for breastfeeding and pregnant females.
How Effective Is Broccoli?
There is limited information to rate the effectiveness of broccoli in following conditions/diseases:
Bladder Cancer - Epidemiologic research demonstrates that the daily ingestion of 1.75 cups of cruciferous vegetables for example cabbage or broccoli lessens the risk of bladder cancer up to 30% in both female and male.
Breast Cancer - Epidemiological research demonstrates that consumption of broccoli is related with a modestly decrease in the potential risk of breast cancer in premenopausal females. But, utilization of broccoli does not appears to be referred with decrease in breast cancer risk in postmenopausal women.
Colorectal Cancer - According to epidemiological research, usage of broccoli may be related with a lessened risk of colorectal cancer.
Prostate Cancer - According to epidemiological research, usage of Brassica vegetables, for example Brussels sprouts, Brassica oleracea, cabbage and cauliflower may be related with a decreased in the risk of prostate cancer. But other epidemiological research has found no link.
Stomach Cancer - Epidemiological research suggests consumption of broccoli might be linked with a reduced risk of stomach cancer.
How Broccoli Works?
The most effective parts of Brassica oleracea are the over the ground parts. Broccoli consists of glucoraphanin, glucosinolate and its subsidiary sulforaphane, which may result in broccoli's purported anticancer action. Some studies propose the sulforaphane bioavailability may be more prominent in uncooked than cooked broccoli. Capacity of broccoli may diminish glucoraphanin content.
Broccoli glucosinolates are metabolized into isothiocyanates and indoles. Indoles may influence estrogen metabolism. Isothiocyanates appear to repress some stage I catalysts. Broccoli also contains glucobrassicin, which is converted into indole-3-caribinole that may also have anticancer impacts.
Broccoli may also restrain expansion of tumor cells.
Broccoli is an excellent source of selenium that may also repress the growth of tumor cells.
Broccoli has antioxidant effects, most likely because of its phenolic components, for example, ferulic acid. Broccoli also contains high vitamin C content. Broccoli's impacts on phase I and phase II proteins might also add to its antioxidant activity. Initial examination recommends that sulforaphane from broccoli lessens oxidative stress in kidney and cardiovascular tissues.
Indole-3-carbinol also appears to have antiviral effects against human papilloma virus (HPV) and herpes simplex infection (HSV).
Some scientists also suggest that indole-3-carbinol may be especially useful against hormone-subordinate malignancies, for example, breast cancer. Indole-3-carbinol induce cytochrome 1A2 (CYP1A2) and P450 1A1 (CYP1A1), which metabolizes estrogen. Estradiol is metabolized to both 2-alpha-hydroxyestrone and 16-alpha-hydroxyestrone. The 16-alpha-hydroxysestrone metabolite has both tumorigenic and genotoxic impacts and is thought to enhance the potential risk of cervical and breast cancer. Indole-3-carbinol shifts metabolism of estradiol from 16-alpha-hydroxyestrone to the weaker estrogen and more benign 2-alpha-hydroxyestrone metabolite, likely offering a defensive impact against hormone-medicated cancer.
Indole-3-carbinol also impels cytochrome P450 2B1, 3A1, 3A2 and 2B2 and in addition phase II enzymes such as quinone reductase, glutathione S-transferase (GST) and uridine diphosphate glucuronide transferase. This results in detoxifying impacts. There are some confirmations that indole-3-carbinol may have other defensive impacts including antioxidant effects and may also result in tumor cell apoptosis and cell cycle abnormalities.
Indole-3-carbinol also seems to have immune modulating impacts. In animal models, high dosage of indole-3-carbinol appears to lessen the natural killer cell effects, but it increases delayed type hypersensitivity in laboratory models. Whether these immune systems impacts add to the impacts of indole-3-carbinol on carcinogenicity is obscure.
Isothiocyanates from broccoli are immediately conjugated with glutathione and afterward metabolized to N-acetylcysteine mixesm, which are eliminated in the urine. N-acetyl components are believed to have anticancer impacts and help decrease the risk of bladder cancer.
Sulforaphane appears to affect the enzyme thioredoxin reductase, which has antioxidant properties. Sulforaphane in combination with selenium causes more induction of thioredoxin reductase than either compound alone. Sulforaphane enhances the effects of stage 2 enzyme which inactivates numerous carcinogens. Sulforaphane may also hinder the effects of phase 1 enzymes for example cytochrome P450 2E1 (CYP2E1) and CYP1A2 which may enhance the carcinogenic activity of some substances.
What Are The Side Effects /Adverse Reactions of Broccoli?
Orally - There is no side effect reported due to the oral consumption of broccoli powder.
Topical application of broccoli may lead to contact dermatitis.
How Broccoli Interacts With Other Herbs and Supplements?
How Broccoli Interacts With Drugs?
No information available.
How Broccoli Interacts With Foods?
No data found.
How Broccoli Interacts With Lab Tests?
How Broccoli Interacts With Diseases and Conditions?
No interaction found.
What Should Be the Dose/Administration of Broccoli?
There is no specific dosage for broccoli.
General Certificate of Analysis (COA)
Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.