Feverfew Purchase & Information
Altamisa, Chrysanthème Matricaire, Featherfoil, Featherfew, Flirtwort Midsummer Daisy, Grande Camomille, Matricaria, Pyrèthre Doré, Partenelle, Pyrèthre Mousse, Santa Maria, Tanaisie Commune, Tanaceti Parthenii CAUTION: Please refer to separate listing for Cornflower, Buttercup
Why Do People Use Feverfew?
Orally - The oral preparations of Canthemum parthenium (Feverfew), such as feverfew powder, are used for resolving a number of ailments like headaches issues, for fever, common cold, cancer, liver disease, earache, vertigo, muscular tension, menstrual irregularities and prevention of migraines, psoriasis, allergies, tinnitus, vomiting and nausea issues. Feverfew powder is also used for anemia, infertility treatment, prevention of miscarriage, arthritis, swollen feet, orthopedic disorders, dyspepsia, asthma, flatulence and diarrhea as well.
Topical preparations of Canthemum parthenium are used for a number of purposes like as an insecticide, antiseptic and for toothache. It is also effective as a general tonic, general stimulant and for intestinal parasites.
Is It Safe To Use?
Possibly Safe - Appropriate, oral and shot term consumption of feverfew powder is considered safe in many cases. Usually feverfew consumption is considered safe for individuals when used for as much as 4 weeks. However, there is not enough information that could explain the safety of feverfew preparations on long term basis.
Likely Unsafe for Pregnant Females - Oral and long term consumption of feverfew powder in pregnancy is considered unsafe. Its utilization may elicit side effects like uterine contractions and may even lead to abortion. That’s why its use is rather contraindicated during pregnancy.
Lactation - Breastfeeding mothers should avoid Canthemum parthenium because there is unreliable information available regarding its safety for breastfeeding females.
How Effective Is Feverfew?
Likely Effective in Migraine Headache - There is some confirmation that oral intake of feverfew powder may decrease migraine headache frequency and also diminish nausea, sensitivity to light and vomiting, which usually follow migraine attacks. It might be more beneficial in patients that suffer regular attacks of migraine headache. But there are some confirmations that suggests that Canthemum parthenium does not benefit patients with migraine. These differences may be due to the different preparations of feverfew used or different method of harvesting them. Combination of feverfew powder, magnesium and riboflavin doesn't appear to diminish the severity and frequency of headache better than placebo.
Likely Ineffective for Rheumatoid arthritis (RA) - Oral consumption of feverfew may not lessen Rheumatoid arthritis symptoms in many cases.
How Feverfew Works?
The most effective part of Canthemum parthenium is its leaves. No less than 39 constituents of feverfew have been isolated and studies. There has been different opinions regarding constituents responsible for pharmacological impacts of feverfew. Parthenolide and sesquiterpene lactone are generally considered the most effective constituents of feverfew.
Parthenolide appears to decrease the production of pro-inflammatory cytokines like tumor necrotic facto (TNF)-alpha and cyclooxygenase-2. It is believed that a minimum 0.2% of parthenolide is needed for decreasing the symptoms of migraine headache. However, a study utilizing alcohol extract of feverfew regularized to contain 0.35% parthenolide was found ineffectual for curing migraine, recommending that parthenolide may not be the active ingredient and that other constituents of feverfew powder maybe important in decreasing the severity and frequency of migraine headache. However, the mechanism through which Canthemum parthenium counteracts headache is still unclear.
It is suggested by clinical studies that extract of feverfew may inhibit discharge of serotonin from leucocytes and platelets and it also restrain platelet aggregation. Feverfew powder may also repress leukotrienes and serum proteases. It also seems to stop prostaglandin synthesis process by inhibiting phospholipase.
Initial studies also suggest that parthenolide and fresh feverfew leaves extract may cause irreversible inhabitation of vascular muscle constriction.
What Are The Side Effects /Adverse Reactions of Feverfew?
Oral - Generally feverfew powder is well tolerated. It may be responsible for gastrointestinal side effects, for example, nausea, heartburn, constipation, diarrhea, bloating and abdominal pain and flatulence. It can also cause nervousness, insomnia, stiffness of joints, dizziness, palpitations, headache, weight gain, tiredness and skin rash. Using feverfew preparations in traditional ways, like chewing fresh leaves, can cause mouth ulceration, swelling of the lips, inflamed oral and tongue mucosa and sometime loss of taste. Mouth ulceration maybe because of sesquiterpene lactone present in feverfew leaves. Various researchers propose that mouth ulceration is a systemic impact. However, another research utilizing dried Canthemum parthenium capsules reported a higher rate of mouth ulcers in subjects taking placebo than feverfew. The symptoms of syndrome that may develop after using feverfew includes migraine, increased irritability and joint and muscle stiffness, sleep deprivation.
Topical - Dermatitis may develop after the oral utilization of Canthemum parthenium.
How Feverfew Interacts With Other Herbs and Supplements?
Supplements and Herbs with Antiplatelet/Anticoagulant Properties - Clinical experiments suggest that feverfew powder may prevent aggregation of platelets. However, these findings are consistent in human beings. Combination of Canthemum parthenium with herbs that affect platelet aggregation could enhance the potential bleeding risk in some individuals. Some of these herbs are turmeric, clove, Panax ginseng, angelica, ginkgo, red clover, danshen, garlic, horse chestnut, ginger, and other herbs.
How Feverfew Interacts With Drugs?
Feverfew may interacts with following drugs and show exacerbated side effects:
• Drugs with Antiplatelet or Anticoagulant properties
• CYTOCHROME P450 1A2 (CYP1A2) SUBSTRATES
• CYTOCHROME P450 2C19 (CYP2C19) SUBSTRATES
• CYTOCHROME P450 2C9 (CYP2C9) SUBSTRATES
• CYTOCHROME P450 3A4 (CYP3A4) SUBSTRATES
How Feverfew Interacts With Foods?
There is no known interaction between feverfew powder and various food items.
How Feverfew Interacts With Lab Tests?
There is no known interaction between Canthemum parthenium and different lab tests.
How Feverfew Interacts With Diseases and Conditions?
Cross-Allergenicity - Feverfew maybe responsible for allergic reactions in people who are sensitive to the plants of Compositae or Asteraceae family. Members of this family include chrysanthemums, marigolds, ragweed, daisies and other plants.
Surgery - Feverfew powder may affect antiplatelet activity in human body. If it is utilized perioperatively, it may be responsible for excessive bleeding. So, patients are advised to stop using feverfew powder at least two weeks before their suggested surgical procedures.
What Should Be the Dose/Administration of Feverfew?
ORAL For migraine, 50 to 100 mg in whole day. Most of feverfew herb extracts utilized in clinical studies had parthenolide content in a percentage of 0.2% to 0.35%, but this does not seems to be effective. Some other studies have also utilized a particular feverfew extract containing supercritical carbon dioxide enriched with parthenolide.
TOPICAL There is no topical dosage of feverfew.
Few feverfew tablet can contain no or little amount of feverfew powder.
General Certificate of Analysis (COA)
Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.