Glucomannan Purchase & Information
Glucomannane, Glucomanano, Konjac Mannan, Konjac
Why Do People Use Glucomannan?
Orally - The oral preparations of Amorphophallus konjac (Glucomannan), like glucomannan powder, are considered to be most effective for constipation issues, type 2 diabetes, weight loss in children and adults, reducing serum cholesterol and to control blood glucose level.
In Food Items - Glucomannan powder is an effective ingredient in many food recipes.
Is It Safe To Use?
Possibly Safe - Oral intake of glucomannan in food items is considered safe. Its flour or glucomannan powder is commonly utilized in Japanese food items in order to improve the taste of noodles. Oral intake of glucomannan encapsulated or powdered form is also considered safe. Amorphophallus konjac can be used for up to four months without serious side effects.
Possibly Unsafe - Tablet form of glucomannan is considered likely unsafe. Some reports of gastrointestinal and esophageal obstruction have been brought to attention due to glucomannan contained tablets. So, patients are advised to take capsules or powder of glucomannan rather than tablets.
Possibly Unsafe for Infants - Glucomannan is considered safe for infants when used orally and appropriately in powdered or encapsulated form. It has been safely used in infant aged up to 4 months.
Lactation & Pregnancy - To rate the safety of glucomannan for breastfeeding and pregnant women, there is lack of authentic and reliable information available.
How Effective Is Glucomannan?
Glucomannan powder is¬ possibly effective in following conditions:
Diabetes - Oral intake of glucomannan appears to lessen blood glucose levels and serum cholesterol in type II diabetic patients. In patients with hyperlipidemia and type 2 diabetes, glucomannan may increase the total amount of serum cholesterol, glycemic control, the levels of low-density lipoprotein (LDL) and systolic blood pressure level. It is also reported that Amorphophallus konjac also increases resistance against insulin syndrome, which is a conditions that appears before diabetes. The constructive effects on resistance against insulin syndrome seem to happen when glucomannan is utilized and mixed with carbohydrate food items.
To rate the effectiveness of glucomannan powder for following conditions, there is lack of reliable information:
Constipation - According to clinical trials, it has been suggested that oral utilization of glucomannan can be helpful to cure constipation. Glucomannan may have bulk laxative impacts because it contains non-absorbable dietary fiber.
Hypercholesterolemia - Glucomannan, when used in an oral dosage of 1.2 grams daily with mixture of chitosan 1.2 grams, daily for a month may lessen total cholesterol level up to 7%, increase high-density lipoprotein (HDL) up to 4% and decrease low-density lipoprotein (LDL) up to 10%.
Obesity - Clinical trials also suggest that oral consumption of glucomannan powder may show desired results for weight reduction in obese adults and children. Some reports also show no effect. Therefore, more confirmations are required for proving the effectiveness of glucomannan in weight reduction.
How Glucomannan Works?
Glucomannan is an un-absorbable polysaccharide made out of mannose and glucose, which is derived from konjac root.
Amorphophallus konjac appears to lessen low-density lipoprotein (LDL) cholesterol levels and serum total cholesterol in adults and healthy men with type 2 diabetes. Glucomannan seems to enhance lipid profile by improving fecal discharge of bile acid and cholesterol. Glucomannan may enhance glycemic control in individuals with type II diabetes likely by increasing the thickness of gastrointestinal contents and slowing gastric emptying. Glucomannan also appears to improve systolic blood pressure level in individuals with type II diabetes.
What Are The Side Effects /Adverse Reactions of Glucomannan?
Gastrointestinal and esophageal obstruction has been reported for when used in form of tablet. So, such patients are recommended to utilized glucomannan in form of capsule or powdered form.
How Glucomannan Interacts With Other Herbs and Supplements?
Hypoglycemia Causing Supplements and Herbs - Preliminary experiments suggest that glucomannan powder may show hypoglycemic effects. Combination of glucomannan and other hypoglycemia causing supplements and herbs reduces the blood glucose levels and may increase hypoglycemia risks in some individuals. Such herbs & supplement include cowhage, bitter melon, goat's rue, ginger, willow bark, kudzu etc.
Vitamin A - Amorphophallus konjac has the ability to lessen absorption of vitamin A and other soluble fat vitamins likely due to the enhancement in bile acids excretion, which helps in the absorption and transport of soluble fat vitamins. It doesn't appears to affect water-soluble vitamins.
Vitamin D - Glucomannan may decrease the vitamin D absorption and other soluble fat vitamins likely due to the enhancement in bile acids excretion, which helps in the absorption and transport of soluble fat vitamins.
Vitamin E - Same effect on vitamin E as that for other fat soluble vitamins (vitamin D, E, A, K).
Vitamin K - Same effect on vitamin E as that for other fat soluble vitamins (vitamin D, E, A, K).
How Glucomannan Interacts With Drugs?
Anti-Diabetic Drugs - Interaction rating between glucomannan powder and anti-diabetic drugs is moderate, so be careful about this combination. This combination may lessen blood glucose levels in those patients who are suffering from type II diabetes and may show additive effects on patient’s glucose levels when utilized with antidiabetes drug therapy. So, such patients should measure their blood glucose level regularly. Some antidiabetes drugs include glyburide (Glynase PresTab, DiaBeta, Micronase), rosiglitazone (Avandia), glimepiride (Amaryl), pioglitazone (Actos), insulin and other drug contained as well.
Oral Drugs - Interaction rating between Amorphophallus konjac and various types of oral drugs is balanced so be careful about this combination. Glucomannan may reduce orally taken drugs absorption including sulfonylurea drugs. Some of sulfonylurea drugs include glimepiride (Amaryl), chlorpropamide (Diabinese), glyburide (Micronase, Glynase PresTab, DiaBeta), glipizide (Glucotrol). Therefore, such drugs should be used 1 hour before or 4 hours after consuming glucomannan powder.
How Glucomannan Interacts With Foods?
There is no known interaction between Amorphophallus konjac and various food items.
How Glucomannan Interacts With Lab Tests?
Cholesterol - Glucomannan powder maybe responsible for decrease in LDL cholesterol, serum total cholesterol and test results in type II diabetic adults and obese adult as well.
Glucose - Amorphophallus konjac may also lessen the concentrations of blood glucose and test results in type II diabetic patients.
Triglycerides - Glucomannan might be the reason for decrease in test results and serum triglycerides in healthy adults.
How Glucomannan Interacts With Diseases and Conditions?
Diabetic patients should be cautious while taking glucomannan because it may lessen blood glucose and may show interaction with anti-diabetic drugs.
Surgery - Glucomannan powder may cause change in blood glucose level. Glucomannan may be responsible for blood glucose control after and during surgical activities. So, patients having blood glucose issues are advised to stop using glucomannan minimum two weeks before elective surgical procedures.
What Should Be the Dose/Administration of Glucomannan?
• For weight loss in adults, 1 gram of glucomannan should be utilized trice in whole day (one hour before each meal) and for weight loss in infants, 2 to 3 grams per day has been used.
• For the treatment of type II diabetes with hyperlipidemia, dosage should be between 3.6 to 10.6 grams in whole day.
• For developing resistance of insulin syndrome, dosage should be between 8 to 13 grams in whole day.
• For hypercholesterolemia, dosage should be 1.2 grams of chitosan along 1.2 grams glucomannan in whole day.
General Certificate of Analysis (COA)
Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.