Yohimbe Purchase & Information

Alternative Names

11-hydroxy Yohimbine, Alpha Yohimbine HCl, Coryanthe Yohimbe, Corynanthe Johimbe, Johimbi, Yohimbehe, Yohimbehe Cortex, Yohimbine, Yohimbine HCl, Yohimbinum Muriaticum

Scientific Name

Pausinystalia Yohimbe

Why Do People Use Yohimbe?

Oral preparations of pausinystalia yohimbe (Yohimbe Bark), like yohimbe powder, are used for impotence, as an aphrodisiac, athletic performance, erectile dysfunction, for exhaustion, weight loss, hypertension complaints, angina, postural hypotension and diabetic neuropathy. Yohimbe powder is also used orally for sexual dysfunction because of selective-serotonin reuptake inhibitors (SSRI), general sexual dysfunction in women and men and as an adjunct to conventional antidepressants for refractory depression. Yohimbe bark is also snuffed or smoked because it has hallucinogenic effects.

Is It Safe To Use?

Possibly Unsafe - Oral usage of Yohimbe powder is considered unsafe. Yohimbe has been related with severe adverse effects such as agitation, cardiac arrhythmia, seizure, myocardial infarction and others. Yohimbine is the basic constituent of Yohimbe, which is regulated as a prescription drug in the North America. There are some confirmations that it can be safe if cautiously used for up to 10 weeks. But because of potentially serious safety concerns, yohimbe should not be taken without any medical supervision. Possibly Unsafe For Children - Oral consumption for infants could possibly be unsafe. Especially those children should avoid yohimbe who are over-sensitive to it. Possibly Unsafe In Pregnancy and Lactation- Oral consumption can lead to various adverse effect for those women who are pregnant or breastfeeding. Yohimbe may have uterine relaxant effects and can result in fetal toxicity.

How Effective Is Yohimbe?

Pausinystalia Yohimbe is possibly effective for following conditions: • Erectile dysfunction (ED) • Sexual dysfunction. To rate the effectiveness of yohimbe for other purposes, there is scarce and unreliable information available.

How Yohimbe Works?

The most effective part of Pausinystalia yohimbe is the bark. The constituent believed responsible for yohimbe's activities is the alkaloid yohimbine. This herb’s bark consist of 6% yohimbine. Sexual enhancer action of yohimbe has been ascribed to genital vein expansion, expanded reflex volatility and nerve impulse transmission to genital tissue in the sacral region. The yohimbine constituent promptly enters the central nervous system (CNS) and works essentially through alpha 2-adrenergic receptor barricade. It also has calcium channel blocking, monoamine oxidase (MOA) inhibiting and peripheral serotonin receptor blocking effects.

What Are The Side Effects /Adverse Reactions of Yohimbe?

The most regularly reported side effects are tachycardia, stomach upset, hypertension, anxiety or agitation, profuse sweating (diaphoresis), flushing, chest pain, tremor, tachypnea, chills or shivering, altered mental behavior or status and mydriasis issues as well. Other symptoms reported in individuals taking Yohimbe powder are insomnia, excitation, salivation, dizziness, irritability, sinusitis, urinary frequency, headache, rash, fluid retention, vomiting and nausea. According to some recent reports most severe side effects include atrial fibrillation, myocardial infarction, renal failure, QT-interval prolongation, seizure amd priapism, issues. There is only one case reported of hypersensitivity reaction including chills, fever, itchy, malaise, progressive renal failure, scaly skin and lupus-like syndrome related with ingestion of a one-day dose of yohimbine. Over dosage of yohimbine constituent can also lead to major toxicity issue such as paralysis, respiratory depression, cardiac failure, cardiac conduction disorders, severe hypotension and even death as well.

How Yohimbe Interacts With Other Herbs and Supplements?

Herbs & Supplements Containing Caffeine - Usage of yohimbe with over dosage of caffeine-containing products or herbs can boost the potential risks of hypertensive crisis. Things containing caffeine are cola, coffee, mate, guarana and tea. Ephedra - Usage of excessive dosage of ephedra can enhance potential risk of hypertensive crisis because there is ephedrine content in yohimbe.

How Yohimbe Interacts With Drugs?

Antihypertensive Drugs - Interaction rating between yohimbe and antihypertensive drugs is moderate, so be careful about this mixture. Usage of yohimbe powder can affect the blood pressure control and should be use cautiously. Clonidine (Catapres) - Interaction rating between clonidine containing drugs and yohimbe is moderate, be careful about this mixture. Avoid concomitant utilization because yohimbine antagonizes the effect of clonidine. Guanabenz (Wytensin) - Interaction rating between yohimbe and drugs containing guanabenz (wytensin) is moderate, so be careful about this mixture. Health advisor do not recommend this concomitant use because yohimbine antagonizes the effect of guanabenz. MONOAMINE OXIDASE INHIBITORS (MAOIS) - Interaction rating between yohimbe and monoamine oxidase inhibitors (MAOIS) is major, so NEVER use this blend. Concomitant use of this drug with yohimbe can result in additive results. Naloxone (Narcan) - Interaction rating between yohimbe and naloxone is moderate, so be careful about this mixture. Concomitant use can have additive therapeutic effects in user. Phenothiazines - Interaction rating between Pausinystalia yohimbe and phenothiazines is moderate, so be careful about this blend. Yohimbe is contraindicated with phenothiazines use because of enhanced risk of alpha 2-adrenergic antagonism. Stimulant Drugs - Interaction rating between yohimbe powder and stimulant drugs is moderate, so be careful about this mixture. Yohimbe is contraindicated because concomitant use may enhance the hypertensive crisis risks because of yohimbe monoamine oxidase inhibitor MAOI activity. Tricyclic Antidepressants (TCAs) - Interaction rating between yohimbe and drugs containing tricyclic antidepressants (TCAS) is moderate, so be careful about this mixture.

How Yohimbe Interacts With Foods?

Tyramine-Containing Foods - Stop using large amounts of food containing tyramine because it can exacerbate the potential risk of hypertensive crisis. Foods containing Tyramine include red wines, fermented meats, aged cheeses and others. Vasopressor-Containing Foods - Large dosage of vasopressor-containing foods should be avoided because of potential risks of hypertensive crisis. Foods containing vasopressor include coffee, overripe fava beans, colas, tea and chocolate.

How Yohimbe Interacts With Lab Tests?

Not known.

How Yohimbe Interacts With Diseases and Conditions?

Angina, Heart Disease - Use of Yohimbe powder is contraindicated in these conditions because of the negative cardiovascular effects. Anxiety - Use of Pausinystalia Yohimbe may lead to anxiety. Benign Prostatic Hyperplasia (BPH) - Yohimbe may exacerbate Benign Prostatic Hyperplasia (BPH) symptoms because of decreased circulation and antagonism of alpha-2 receptors. Depression - Yohimbine may elicit mania-like symptoms in suicidal tendencies in individuals with endogenous depression or persons suffering from bipolar depression. Some other diseases or conditions which may be effected by using yohimbe are: • Diabetes • Hypertension • Hypotension • Kidney Disease • Liver Disease • Post-Traumatic Stress Disorder (PTSD) • Schizophrenia • Yohimbe Hypersensitivity

What Should Be the Dose/Administration of Yohimbe?

ORAL For the treatment of sexual dysfunction issues such as impotence, yohimbe is typically used in a dose giving yohimbine within the range of 15 to 30 mg every day. Amount of yohimbine up to 100 mg every day have been used.

Comments

It is an evergreen tree that is native to Zaire, Gabon and Cameroon. The bark part of the yohimbe tree contains the alkaloid yohimbine.

General Certificate of Analysis (COA)

Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.