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Cats Claw: Overview of Purchase & Information

Alternative Names

G
Griffe Du Chat
L
Life-Giving Vine of Peru, Liane du Pérou
S
Samento
U
Uña De Gato

Caution
Make sure you see separate listing for Cat's Foot.

Scientific Name

Scientific names for cats claw are Uncaria tomentosa and Uncaria guianensis. Cats claw belongs to Rubiaceae family of plants.

Why do People use Cats Claw?

Oral
The oral preparations of Uncaria guianensis (Cats Claw), like cats claw powder, are typically used for peptic ulcers, diverticulitis, gastritis, colitis, parasites, hemorrhoids, leaky bowel syndrome and Alzheimer's disease. Other uses of cats claw are for the treatment of herpes simplex, viral infections, chronic fatigue syndrome (CFS), human immunodeficiency virus (HIV), arthritis, wound healing, allergic rhinitis issues, asthma, gonorrhea, glioblastoma, for birth control, dysentery, cleansing the kidneys and bone pain problems.

Is Cats Claws Safe to Use?

Possibly Safe
Cats claw powder is likely safe when taken orally for short period. Particular freeze-dried extract of cats claw appears to be safe when utilized for maximum 4 weeks. Another extract with combination of oxindole alkaloids is reported safe for up to 24 weeks utilization.

Likely Unsafe for Pregnant Females
Oral consumption of Uncaria guianensis is considered unsafe for pregnant women; so avoid using it during this stage.

In Lactation
No information available.

How Effective is Cats Claw?

Likely Effective for Osteoarthritis
Taking a particular freeze-dried cats claw extract, possessing Uncaria guianensis, orally seems to diminish pain of knee related to physical movement within one week of treatment, however it doesn't lessen pain at rest or mitigate swelling of knees.

Likely Effective for Rheumatoid Joint Pain (RA)
Taking orally a particular extract of cats claw (Uncaria tomentosa), containing pentacyclic oxindole alkaloids however free of tetracyclic oxindole alkaloids, seems to improve rheumatoid arthritis (RA) symptoms. Taking orally in blend with hydroxychloroquine or sulfasalazine for continuously 24 weeks, cats claw powder appears to decrease the number of joints with pain and swelling in them.

However in order to rate safety for other uses, there is lack of authentic information.

What is the Mechanism of Action of Cats Claw?

Most effective parts of Uncaria guianensis are its bark and roots. Rhynchophylline is thought to be the major alkaloid of cats claw. There are some confirmations that it may have cardiovascular impacts including lowering heart rate, dilating peripheral blood vessels and possibly lowering level of blood cholesterol. Rhynchophylline may also lessen the activity of sympathetic nervous system.

According to some clinical experiments, cats claw powder is thought to work for osteoarthritis because of its anti-inflammatory impacts. It appears to suppress the production tumor necrosis factor-alpha (TNF-alpha) and prostaglandin E2. There is interest toward utilizing cats claw for rheumatoid arthritis. The immunomodulatory effects are reported due to alkaloids of pentacyclic oxindole found in cats claw, which increase lymphocyte and phagocytosis activity.

Uncaria guianensis has shown to stimulate the production of colony-stimulating elements, IL-6, interleukin-1 (IL-1) and myelopoiesis enhancement in animal models. It also builds the number of blood cells including B and T lymphocytes, granulocytes and natural killer (NK) cells in animal model. But cats claw does not appear to change these cells proportion. Also, cats claw does not appear to expand precursors (germ cells) of the cells, proposing that it delays white blood survival instead of expanding production of cell.

Are there Side effects of Cats Claw?

Side effects seen with the use of cats claw powder include:
• Headache
• Vomiting
• Dizziness

How Cats Claw Interacts with Herbs and Supplements?

Supplements & Herbs with Hypotensive Effects
Use of cats claw powder may have hypotensive effects. Combination of cats claw and other supplements and herbs that possess hypotensive impacts may enhance the potential risks of hypotension. Some of these supplements & herbs consist of casein peptides, andrographis, fish oil, coenzyme Q-10, lycium, L-arginine, theanine, stinging nettle and other supplements & Herbs.

How Cats Claw Interacts with Drugs?

Antihypertensive Drugs
Interaction between antihypertensive drugs and cats claw in moderate so be careful of this combination. This interaction may be responsible for lowering blood pressure so patients should be advised to discontinue cats claw with combination of antihypertensive drugs.

Cytochrome Substrates
Interaction rating of Uncaria guianensis and cytochrome substrates is moderate so be careful of this mixture. Some initial experiments recommend that cats claw powder can inhibit cytochrome enzymes. Combination of cytochrome substrates and cats claw may enhance the level of metabolized drugs, however this reaction has not been observed in human beings. Cytochrome substrates drugs include ketoconazole (Nizoral), triazolam (Halcion), lovastatin (Mevacor), fexofenadine (Allegra), itraconazole (Sporanox) and a number of other drugs.

Immunosuppressants
Interaction rating of cats claw powder and Immunosuppressants is moderate so be careful of this combination. Cats claw powder may inhibit the effects of immunosuppressant therapy because of its immunostimulating activity. It stimulates phagocytosis and enhances mobility of leukocytes and improves cellular respiratory. Drugs in the category of immunosuppressant drugs includes basiliximab (Simulect), azathioprine (Imuran), daclizumab (Zenapax), cyclosporine, mycophenolate (CellCept), muromonab-CD3, prednisone (Deltasone, Orasone), sirolimus (Rapamune), tacrolimus (Prograf, FK506) and other corticosteroids drugs.

How Cats Claw Interacts with Foods?

There is no known interaction between cats claw and other food items.

How Cats Claw Interacts with Conditions and Diseases?

Autoimmune Diseases
There is a problem that cats claw may show side effects in patients with autoimmune diseases due to its immune stimulating potential. Patient suffering from systemic lupus erythematosus (SLE), multiple sclerosis or some other autoimmune diseases should avoid using Uncaria guianensis without any further recommendation of their physician.

Hypotension
Some diseases like hypotension may be exacerbated by the regular use of cats claw powder.

Leukemia
Initial clinical experiments recommend that cat claw powder may extend survival time of leukemia cell in childhood. It is also reported that cat claw may worsen disease in those patients who are suffering from leukemia. So, such patient should discontinue the use of cats claw.

Surgery
It is reported that cats claw may put adverse effects on blood pressure level. It may be responsible for abnormal control of blood pressure after and during surgical process. So patients should be advised to stop using Uncaria guianensis minimum two weeks before their elective surgical process.

What should be the Administration / Dosage of Cats Claw?

• In order to cure osteoarthritis of knee, 100 mg of freeze-dried liquid extract of cats claw should be utilized.
• For the treatment of rheumatoid arthritis, 60 mg of cats claw specific extract should be used every day in three equally divided doses.

Comments

In 1997 cat claw was the most known herbs in the United States and was ranked 17th most effective herbs. There are two species of cats claw that are used for medicinal purpose, which are Uncaria guianensis and Uncaria tomentosa. Uncaria guianensis is well known in the European countries and Uncaria tomentosa is famous in the US.

General Certificate of Analysis (COA)

General certificate of analysis contains necessary information regarding the product. Once you buy a product, you get a general certeficate of analysis with it that mentions necessary information like the date of manufacture of the product and its batch number. If the product you get doesn’t have its batch number or date of the manufacture mentioned, please make sure to ask us for the general certificate of analysis. For that purpose you can simly mail us asking for the COA using your email ID. The COA will be mailed to you within short period of time. The whole sale prices of different products vary so do ask for the whole sale price of 25 kilos or more of any product that you buy. To get the desired product, please be sure to mention necessary inforamtion like the scientific name of the product, its trade name its designated ID.


SKU 637 Cats Claw Product Purchase

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