Pomegranate Purchase & Information
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Why Do People Use Pomegranate?
Oral preparations of Punica granatum (Pomegranate), like pomegranate powder, is used for the treatment of congestive heart failure (CHF), hypertension, atherosclerosis, myocardial ischemia, hyperlipidemia, hypertension, hemorrhage, swine flu, influenza, periodontal disease, stomatitis, neonatal ischemia, erectile dysfunction, HIV disease and opportunistic intestinal worms. It is also used for obesity and weight loss, for preventing prostate cancer, for diarrhea and dysentery, as an astringent and as an abortifacient. Other applications of pomegranate are used for menopausal symptoms, acidosis, tapeworm infestations, chronic obstructive pulmonary disease (COPD), to treat cancer and diabetes.
Topically - Pomegranate is also used as a sore throat gargle and to treat hemorrhoids.
Is It Safe To Use?
Likely Safe - Safety of pomegranate fruit juice is safe when taken orally for appropriate time period. Pomegranate juice has been safely utilized in studies lasting up to three years.
Extract of pomegranate is also used orally and for appropriate time period. Another particular extract of pomegranate, ellagitannin-enriched polyphenol, should be consumed in a dose of 1420 mg per day. It can be safely used for up to four weeks. However, studies have shown that pomegranate extract is used topically on oral mucosa also shown apparently safe results.
Possibly Unsafe - Recent studies have shown that stems and root of pomegranate has severe side effects when utilized in excessive amount and taken orally because there is toxic alkaloid pelletierine in the root.
Possibly Safe in Pregnancy and Lactation - Orally and appropriate usage of fruit or fruit juice is highly recommended for breast feeding and pregnant females. However, extract of pomegranate should be avoided in both conditions because there is scarce and unreliable information about extract safety.
How Effective Is Pomegranate?
In following conditions pomegranate seems to be effective:
• Chronic Obstructive Pulmonary Disease (COPD)
There is limited and unreliable information about effectiveness of pomegranate in following conditions:
• Coronary heart disease
• Prostate cancer
More confirmations are required to rate the safety of pomegranate for other purpose.
How Pomegranate Works?
The most effective parts of Punica granatum are the fruit, fruit juice, seed oil, seed, rind, bark, stem, root, flower and leaf. The seed oil consist of polyphenols and different fatty acid including palmitic acid, punicic acid, oleic acid, stearic acid and linoleic acid. Number of seed constituents have antioxidant activity in vitro.
Pomegranate leaves, bark and fruit husk additionally contain large amount of gallotannins and ellagitannins.
In addition to pomegranate juice and polyphenols also include ascorbic acid, citric acid, tartaric acid and oxalic acid.
Estrone and number of other nonsteroidal estrogenic substances exist in the seeds of pomegranate.
The pomegranate flower has been utilized in Eastern customary pharmaceutical to treat diabetes. According to initial studies flower of pomegranate has alpha-glucosidase repressing activity.
Initial studies also suggest that pomegranate juice may lessen the atherosclerosis progression. The antioxidant impacts may add to diminished macrophage action in atherosclerotic plaques and decrease lipid peroxidation of low-density lipoproteins (LDL).
Pomegranate leaves consist of tannins. A leaves extract of pomegranate is thought to have anti-obesity and anti-hyperlipidemic effects, perhaps by diminishing energy consumption and inhibiting pancreatic lipase. In animal model of obesity, leaves extract of pomegranate decreases caloric intake, body weight and serum levels of cholesterol and triglycerides.
Research also proposes that pomegranate juice can enhance the nitric oxide synthetase effects in the blood vessel endothelium. Nitric oxide synthetase builds the accessibility of nitric oxide, an vasodilator and antioxidant.
Pomegranate juice may diminish cholesterol because of its polyphenol constituents. It is said that polyphenols may diminish cholesterol synthesis in the liver.
Pomegranate juice can decrease the effects of angiotensin converting enzyme (ACE) and lessen blood pressure level in patients with hypertension. The serum effects of ACE is diminished more or less 36%, with incremental declines happening in patients officially taking angiotensin converting over catalyst inhibitors (ACEI).
According to initial studies pomegranate juice may have action against HIV. Its constituents appear to target the viral envelope and prevent viral entry into the cells.
Juice of pomegranate seems to be more effective more against colon, oral and prostate cancer cells in vitro than its individual constituents.
It is also proposed that pomegranate may be useful for beauty care products purposes for aging skin.
What Are The Side Effects /Adverse Reactions of Pomegranate?
Generally there is no major side effect reported due to oral consumption of pomegranate.
Pomegranate seeds or fruit may result in allergic reactions. Such allergic reactions happen usually in people who are allergic to other plants. There is one case report where patients experienced pomegranate-dependent, exercise-induced anaphylaxis. The patient enrolled with lip edema and widespread urticaria (hives) after ingesting pomegranate seeds and then exercising.
Topical consumption of pomegranate may result in contact hypersensitivity such as angioedema, urticaria, red itchy eyes, rhinorrhea and dyspnea arising within a few minutes of exposure.
How Pomegranate Interacts With Other Herbs and Supplements?
Following herbs and supplements may interact with Punica granatum:
• Hypotensive Herbs & Supplements
How Pomegranate Interacts With Drugs?
Pomegranate powder may interact with following drugs:
• Ace Inhibitors (ACEIs)
• Antihypertensive Drugs
• Carbamazepine (Tegretol)
• Cytochrome Substrates
• Rosuvastatin (Crestor)
• Tolbutamide (Orinase)
• Warfarin (Coumadin)
How Pomegranate Interacts With Foods?
How Pomegranate Interacts With Lab Tests?
How Pomegranate Interacts With Diseases and Conditions?
Following are those conditions or diseases which may interact with pomegranate powder:
• Plant Allergies
What Should Be the Dose/Administration of Pomegranate?
ORAL For reduce the hypertension, 50 mL of pomegranate juice should be consumed every day.
To treat hyperlipidemia, 40 grams of concentrated pomegranate juice should be orally used on daily basis.
To protect from coronary heart disease, pomegranate juice should be used daily with amount of 240 mL (about 8 ounces).
For prostate cancer, juice of pomegranate should be ingested 240 mL (8 ounces) daily.
To treat atherosclerosis, pomegranate juice 50 mL per day has been used.
Pomegranate (Punica granatum) is different in the botanical kingdom. The main other plant in its family is a small tree that grows exclusively in Yemen’s island. It has been utilized for centuries to treat a wide mixture of diseases. It is in Hebrew, Greek, Islamic, Buddhist and Christian writings and mythology.
General Certificate of Analysis (COA)
Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.