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Rue Purchase & Information

Alternative Names

Common Rue, Garden Rue, German Rue, Herb-of-Grace, Herbe à la Belle-Fille, Herbe de Grâce, Herbe de Repentance, Herbe de la Rue, Herbygrass, Raute, Ruda, Ruda de Castilla, Rue Fétide, Rue des Jardins, Rue Officinale, Rue Puante, Ruda, Ruta Grav, Ruta graveolens, Rutae Folium, Rutae Herba, Sudapa CAUTION: Please refer to separate listing for Goat's Rue

Scientific Name

Ruta Graevolens

Why Do People Use Rue?

The oral preparations of Ruta graveolens (Rue), like rue powder, are used as uterine stimulant and abortifacient, for menstrual disorders and discomforts, fever, as antispasmodic, antifungal, hysteria, cramps, feverish, antibacterial, infectious diseases, diarrhea, hepatitis, headaches, pleurisy, weakness of the eyes and neuralgic afflictions. It is also utilized orally for arthritis, respiratory complaints, epilepsy, cancer of the mouth, intestinal worm infestations, Bell's palsy and multiple sclerosis. Rue powder is also used orally as a diuretic, for dyspepsia, for loss of appetite, arteriosclerosis, circulatory disorders, nervousness, heart palpitations, as a contraceptive agent and hemostatic. Topically - It can be used topically for dislocations, arthritis, injuries of the bone, sprains, warts, oral and pharyngeal cavities, inflammation of the skin, toothaches, earaches, tumors, headaches and as an insect repellent. In Foods and Beverages - Rue and its oil are consumed as flavor agent in various beverages and food items. In Manufacturing Practices - Rue oil is used as a fragrance in cosmetics and soaps products.

Is It Safe To Use?

Likely Safe - Oral consumption in amounts generally found in foods is considered safe. In the United States, Rue and rue oil have attained Generally Recognized as Safe (GRAS) status. Likely Unsafe - Fresh rue have reported various side effects when utilized orally for medicinal purposes. Fresh rue can leads to serious liver and kidney damage. Likely Unsafe Pregnancy - Pregnant women should avoid oral consumption of rue because it may have antiabortion and uterine stimulant effects. Avoid In Lactation - Breastfeeding females should also avoid oral consumption of rue powder when used in medicinal amounts.

How Effective Is Rue?

To rate the effectiveness of rue powder, there is less authentic and unreliable information found.

How Rue Works?

The most effective parts of Ruta graveolens are the aerial parts. Rue contains arborinine, arborine, furocoumarins rutamarin, gamma-fagarine, xanthotoxin and bergapten. The furocoumarins and the alkaloids have reversible anti-inflammatory, antihistaminic properties and spasmolytic activity. The furocoumarins may also have phototoxic, photosensitizing, mutagenic impacts and may lead to skin related issues. The constituent chalepensin may have hostile and antifertility impacts. Rue oil has anthelmintic effects, likely because of the constituent 2-undecanone, this constituent can also cause premature births (abortion). In spite of the fact that rue oil isresponsible for lethal adrenal, kidney and liver failure, daily consumption of 30 mg rue for consecutively three months doesn’t cause these side effects The impacts of rue extract on neuromuscular conditions are thought to result from potassium channel blocking in myelinated nerve cells.

What Are The Side Effects /Adverse Reactions of Rue?

Oral consumption of rue can lead to melancholic mood, GI irritation, tiredness, sleep disorders, spasms, dizziness, and serious liver damage and severe kidney. The fresh leaves juice can cause fainting, painful stomach and intestinal irritation, bradycardia, clammy skin, lethargy, swelling of the tongue and abortion related issues. Rue oil can be responsible for vomiting, severe stomach pain, confusion, exhaustion and convulsions. Excessive dosage of rue oil more than 100 mL or its leaves over 120 grams can cause systemic complications, violent gastric pain, vomiting complaints and even cause death. Contact dermatitis and phototoxic reactions such as skin blisters may appear with topical exposure to the rue-containing products and fresh plant followed by exposure to sunlight.

How Rue Interacts With Other Herbs and Supplements?

Goldenseal - There are some reports regarding controlling the side effects of over dosage of rue by administration of goldenseal, yet these findings are not confirmed.

How Rue Interacts With Drugs?

Photosensitizing Drugs - Interaction rating between Ruta graveolens and drugs containing photosensitizing contents is moderate, so be careful about this mixture. Rue powder may enhance the potential risks of phototoxic response to PUVA therapy because of its 5-methoxypsoralen content. There is one case reported about enhanced phototoxic side effects to PUVA therapy related with ingestion of a rue therapy. Drugs utilized in PUVA therapy including Trioxsalen (Trisoralen) and methoxsalen (8-methoxypsoralen, 8-MOP, Oxsoralen). Rue may also enhance the potential risks of photo-toxicity when orally used with combination of other drugs that may responsible for photosensitivity. There are few other drugs that may responsible for photosensitivity such as sulfa drugs (Septra, Bactrim, others), quinolones (Ciprofloxacin, others), amitriptyline (Elavil) and tetracycline.

How Rue Interacts With Foods?

Not known.

How Rue Interacts With Lab Tests?

Not known.

How Rue Interacts With Diseases and Conditions?

Rue may enhance the potential risks of phototoxic response to PUVA therapy because of its 5-methoxypsoralen content. Drugs utilized in PUVA therapy include Trioxsalen (Trisoralen) and methoxsalen (8-methoxypsoralen, 8-MOP, Oxsoralen). Rue may also enhance the photo-toxicity risk when utilized with other drugs that may responsible for photosensitivity. Some other drugs that cause photosensitivity include quinolones (Ciprofloxacin, others), amitriptyline (Elavil), tetracycline and sulfa drugs (Bactrim, Septra, others).

What Should Be the Dose/Administration of Rue?

ORAL Usually people orally use 500 mg of crushed rue. However, physician suggest dosage of 1 grams daily. Rue is also used as a tea, mix one teaspoon of rue powder one cup of boiling water to make this tea. Take one cup of this tea daily. TOPICAL There is no topical dosage of rue.


Don’t mix this with meadow rue (Thalictrum species) and goat's rue (Galega officinalis).

General Certificate of Analysis (COA)

Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.

Specification Sheets

Rue Powder


These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

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