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Sangre de Grado Purchase & Information

Alternative Names

Blood of the Dragon, Drago, Dragon's Blood, Lan-Hiqui, Laniqui, Sang de Dragon, Sangre de Drago, Sangre de Dragon, Sangue de Agua, Sangue de Drago, SP 303, SP-303, Taspine CAUTION: Please refer to separate listings for Dragon's Blood and Herb Robert

Scientific Name

Croton lechleri

Why Do People Use Sangre de Grado ?

Sangre de grado is also referred to by its scientific name croton lechleri or its constituent named as SP-303. There oral preparations of sangre de grado, such as sangre de grado, are used for AIDS, cholera, cancer treatment, traveling, irritable bowel syndrome (IBS) and Clostridium difficile infection. It is also used orally for treating viral respiratory infection and supporting the body’s tissue repair mechanisms, for oropharyngeal and gastrointestinal ulcers, hemorrhage, fever, fractures, bleeding gums, hemorrhoids, wound healing, insect bites and stings, eczema, for vaginal baths before childbirth, vaginitis and as a general tonic. Topically - Sangre de grado or its essential constituent such as SP-303 are utilized for treating herpes simplex virus (types 1 and 2).

Is It Safe To Use?

Possibly Safe - Oral consumption sangre de grado, which contain SP-303 constituent, is safe when utilized topically, appropriately and orally. Avoid in Pregnancy & Breast Feeding - Pregnant and breastfeeding females should avoid and oral and topical consumption of sangre de grado.

How Effective Is Sangre de Grado ?

Sangre de prado have possibly effective results for following conditions: • AIDS-Related Diarrhea • Herpes Simplex Virus (HSV) • Traveler's diarrhea

How Sangre de Grado Works?

Croton lechleri is a local tree of Amazon in South America. It is also known as sangre de monster. The resin, a thick red latex, and bark have a long history of topical and oral medicinal uses. Sangre de grado powder may also have antibacterial, anti-tumor, anti-inflammatory, antiseptic and anti-hemorrhagic properties. Topically, it has been demonstrated to lessen swelling, vasodilation and secretory reaction to irritation, protect hyperalgesic reactions and better the mucosal healing in research. There are a number of active constituents of sangre de grado including tapsine and SP-303. According to initial studies, constituent SP-303 may influence on diarrhea by restraining cyclic adenosine monophosphate (cAMP), which leads to fluid and chloride discharge. SP-303 reveals reaction against type one and two herpes simplex viruses respiratory syncytial virus (RSV) and flu An infection is likely by hindering viral entrance into cells.

What Are The Side Effects /Adverse Reactions of Sangre de Grado ?

No severe side effect or lab abnormalities have been reported in clinical studies using the sangre de grado derivative SP-303. Topical application of sangre de grado may lead to SP-303 can lead to burning and local pain.

How Sangre de Grado Interacts With Other Herbs and Supplements?

None known.

How Sangre de Grado Interacts With Drugs?

None known.

How Sangre de Grado Interacts With Foods?

None known.

How Sangre de Grado Interacts With Lab Tests?

None known.

How Sangre de Grado Interacts With Diseases and Conditions?

Leukemia - Taking sangre de grado may adversely affect disease activity in patients suffering from leukemia. Such patients are suggested to stop using sangre de grado.

What Should Be the Dose/Administration of Sangre de Grado ?

ORAL For curing AIDS’s diarrhea, extract of sangre de grado containing 500 mg of SP-303 (SB-Normal Stool Formula) every six hours has been utilized. For curing traveler's diarrhea, extract of sangre de grado containing SP-303 within the range of 125 to 500 mg (SB-Normal Stool Formula) should be used four times every day f for two days.


SP-303 was in Phase III clinical trials with "fast track" designation for Phase II trials for traveler's diarrhea and AIDS-related diarrhea treatment.

General Certificate of Analysis (COA)

Specification sheet links below are a standard copy of the COA less the batch or lot number and manufactures dates. Specification sheet can be dated and should only be considered as a general information. Please contact and request an up to date COA if needed for specific updated information before placing order by filling out the contact form with product name and SKU number. If ordering quantities of twenty five kilos or more contact for availability.

Specification Sheets

Sangre de Grado Powder


These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

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